“Stereochemistry: Principles and Practice” offers a comprehensive exploration of the field of stereochemistry, focusing on both fundamental concepts and their practical applications. Designed for students, educators, and professionals, this book serves as an essential resource for understanding how the spatial arrangement of atoms influences molecular behavior, reactivity, and interactions. It provides a detailed look at key concepts such as isomerism, chirality, optical activity, and stereochemical reactions, while also covering advanced topics that highlight the significance of stereochemistry in real-world applications. The book begins with an introduction to the core principles of stereochemistry, including symmetry elements, molecular conformations, and the concept of chirality. It then progresses to examine stereoisomerism, the nature of enantiomers and diastereomers, and how these are important in various chemical reactions. The text also delves into stereochemical reactions such as nucleophilic substitution, electrophilic addition, and the role of stereoselectivity and stereospecificity in these processes. A strong emphasis is placed on the applications of stereo chemistry in fields such as pharmaceuticals, agrochemicals, and material science, demonstrating its relevance in drug development, green chemistry, and nanotechnology. The book explores how understanding stereochemistry is crucial in designing effective drugs, optimizing industrial processes, and addressing environmental concerns. In addition, “Stereochemistry: Principles and Practice” incorporates the latest techniques and technologies used to study stereochemistry, such as NMR spectroscopy, X-ray crystallography, and computational chemistry. These tools enable a deeper understanding of molecular structures and their behavior, making the book an indispensable reference for those working in chemistry, biochemistry, pharmacology, and related fields. Overall, this book offers a well-rounded approach to stereochemistry, bridging theory and practice, and providing valuable insights into one of the most vital areas of modern chemistry.