Evolution of an existing drug molecule from a conventional form to a novel delivery system can significantly improve its performance in terms of patient compliance, safety and efficacy. In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. An appropriately designed Novel Drug Delivery System can be a major advance for solving the problems related towards the release of the drug at specific site with specific rate. A novel drug delivery system refers to strategy, technology, formulation based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. This book has been written in accordance with the current syllabus prescribed for B.Pharma students. Keeping in view the requirements of students and teachers, this book has been written to cover all the topics in an easy-to-comprehend manner, and it provides the students fundamentals of novel drug delivery system, polymers used, their formulation and evaluation which are required by them during their pharmaceutical career.