Quintessence of Pharmacovigilance refers to the research and practises involved in the identification, evaluation, comprehension, and avoidance of unfavourable effects or the any other potential drug-related issues. The most fre- quent way to gather safety data is through the spontane- ous-reporting of adverse occurrences and adverse medica- tion responses. A substance is equal to a danger when con- sumed. Consumption of medications is only acceptable when the benefits outweigh the risks. Therefore, the benefit to risk ratio of a medicine determines whether it should be used or not. Due to the individualization of pharmaceuticals for each patient, it is up to the doctor’s clinical judgement to choose what will be best for the patient. Observations pertaining to pharmacovigilance can also be used to determine the risk connected to the medicine. Studies on pharmacovigilance provide information on potential dangers connected to a certain medication. Even drugs have the potential to cause unpleasant effects, whether intentional or not. The only scenario in which this generalisation does not apply is when a medication is prescribed because the body lacks certain nutrients, such as certain vitamins or minerals. As the investigation of potential negative effects of medications, this forms the core of pharmacovigilance.