Systems for administering medications intravenously or systemically are known as “drug delivery systems.” Methods of administration, such as oral medication or intramuscular injections, are examples of these technologies. The term “drug delivery system” may also be used to refer to the ‘packaging’ of pharmaceuticals, such as a micelle or a nanoparticle, that prevents the medication from degrading and facilitates its transport to its intended site of action in the body. Breakthroughs in medication delivery have occurred during the last several decades, and even more, exciting developments are expected soon. Biomedical engineers have made significant strides in our knowledge of the physiological obstacles to effective drug administration and in the creation of various innovative mechanisms of drug delivery that have been used in clinical practise. Despite this advancement, many existing medicines for illness still come with undesirable side effects. Drug interactions with healthy organs or tissues may lead to unwanted side effects, reducing the effectiveness of treatment for many conditions, including cancer, neurological illnesses, and infectious diseases. As research and development in this area continue, it will become easier to provide medications precisely where they are needed, reducing the likelihood of unwanted reactions. Traditionally, doctors have tried to treat just the symptoms of sickness. Some medications may be delivered locally rather than systemically, which can reduce drug toxicity and adverse effects while increasing the effectiveness of therapy.